- Basic knowledge of genetics and forensic science
- Familiarity with DNA sequencing concepts
Audience
- Forensic scientists and geneticists
- Anthropologists and bioarchaeologists
- Law enforcement and forensic investigators
Next Generation Sequencing (NGS) has revolutionized forensic genetics and anthropology by enabling high-throughput DNA analysis for human identification, ancestry inference, and forensic casework.
This instructor-led, live training (online or onsite) is aimed at advanced-level forensic scientists, geneticists, and anthropologists who wish to apply NGS techniques to forensic investigations.
By the end of this training, participants will be able to:
- Understand the principles of NGS and its forensic applications.
- Analyze forensic DNA samples using NGS techniques.
- Interpret NGS data for human identification and ancestry determination.
- Utilize NGS in degraded and complex DNA samples.
- Apply bioinformatics tools for forensic genomic analysis.
- Understand legal and ethical considerations in forensic genomics.
Format of the Course
- Interactive lecture and discussion.
- Lots of exercises and practice.
- Hands-on implementation in a live-lab environment.
Course Customization Options
- To request a customized training for this course, please contact us to arrange.
Introduction to NGS and Forensic Applications
- Overview of DNA sequencing technologies
- Advantages of NGS over traditional forensic methods
- Common forensic applications of NGS
Fundamentals of Forensic Genetics
- DNA markers used in forensic analysis
- Short Tandem Repeats (STRs) and Single Nucleotide Polymorphisms (SNPs)
- Mitochondrial DNA and Y-chromosome analysis
NGS Workflows in Forensic Casework
- Sample preparation and library construction
- Sequencing protocols for forensic samples
- Quality control and contamination prevention
Bioinformatics and NGS Data Analysis
- NGS data processing and alignment
- Variant calling and forensic interpretation
- Software tools for forensic genomic analysis
Forensic Anthropology and Ancestry Determination
- Genetic markers for ancestry and population studies
- NGS applications in ancient and degraded DNA analysis
- Case studies in forensic anthropology
NGS for Challenging and Degraded Samples
- Techniques for low-quality and low-quantity DNA
- Dealing with environmental and mixed DNA samples
- NGS applications in missing persons and disaster victim identification
Legal, Ethical, and Regulatory Considerations
- Privacy concerns in forensic genomics
- Regulatory frameworks for forensic DNA databases
- Ethical challenges in forensic genetic analysis
Future Trends in Forensic Genomics
- Advancements in sequencing technology
- Integration of AI in forensic genetics
- Emerging forensic applications of NGS
Summary and Next Steps
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